Measuring salivary cortisol levels
How can the answer be improved?A flattened amplitude of cortisol circadian variation, low morning cortisol levels or excessive cortisol levels can all result from ongoing stress (and thus can cloud group results). measuring salivary cortisol levels
Salivary cortisol is an objective measure of stress and is known to accurately reflex serum cortisol, however it has not been well characterized in PD. Better characterization in PD could assist in future studies examining the interplay of emotional stress and stress reduction in PD.
Salivary Cortisol. Cortisol is actively involved in the regulation of calcium absorption, blood pressure maintenance, antiinflammatory function, gluconeogenesis, gastric acid, pepsin secretion, and immune function. (1, 2, 3) Cortisol production has a circadian rhythm. (4) Levels peak in the early morning and drop to the lowest concentration at night. How to test for salivary cortisol. A normal range for salivary cortisol levels is 20 to 25 nanomoles per liter (nmolL) in the morning. The salivary cortisol levels decrease throughout the day. Many labs offer interpretation of the salivary cortisol lab results, but its imperative that you discuss the results with your healthcare practitioner.measuring salivary cortisol levels Baid SK, Sinaii N, Wade M, et al. Radioimmunoassay and tandem mass spectrometry measurement of bedtime salivary cortisol levels: a comparison of assays to establish hypercortisolism. J Clin Endocrinol Metab 2007; 92: 3102. Evans PJ, Peters JR, Dyas J, et al. Salivary cortisol levels in true and apparent hypercortisolism.